ESE

ESE or Ese may refer to:

• East-southeast, a cardinal direction
• ESE (teaching), Exceptional Student Education
• Easy Serving Espresso Pod
• Ethical Sensory Extrovert
• European School of Economics
• European Society of Endocrinology
• Exonic splicing enhancer, an RNA sequence which guides splicing machinery
• Extensible Storage Engine
• Ese, a village in Sogn og Fjordane, Norway
• Early Streamer Emission, a type of lightning protection system